| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D463-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D463-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate |
1988-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9ee8e4fc36981ef878f3e8a38363cb5 |
| publicationDate |
1989-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0308123-A1 |
| titleOfInvention |
Crystalline antibiotic intermediate |
| abstract |
Crystalline p-nitrobenzyl 7β-phenoxyacetylamino-3-hydroxy-1-carba(dethia)-3-cephem-4-carboxylate and the crystalline mono-acetic acid solvate thereof are provided by mixing a carboxylic acid or a sulfonic acid with a solution of the 3-hydroxy ester in DMF or DMAC. Acetic acid provides the crystalline acetic acid solvate while other acids provide crystalline non-solvated 3-hydroxy ester. The crystalline forms are useful purified intermediates to antibiotics. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6001996-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0637587-A1 |
| priorityDate |
1987-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |