abstract |
The xantosulfonamido and benzensulfonamido derivatives corresponding to the formula:n wherein X represents an alkyl-alkoxy halogen, Y represents an alkyl-alkoxy-halogen and Z represents the groupn or Y and Z taken together form the group:n wherein R₁ in turn is a group selected among electron attracting groups, halogens and the group:n possess activity in inhibiting the aldose-reductase enzyme system and are thus useful in the treatment of the complications , at the eye and peripheral neuropathy levels, as induced by diabetes. |