http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0307854-A2

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-056
filingDate 1988-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a7577bacdae6e3abe57ab48fc64e870
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2caddcbd415c7c033354e33f7aeb4144
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publicationDate 1989-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0307854-A2
titleOfInvention High-temperature method for the production of ribavirin
abstract A method for the production of a 1,2,4-tria­zole nucleoside comprising the step of reacting a ribose donor with a triazole compound in the presence of an enzyme preparation derived from Brevibacterium acetylicum is disclosed. The method is characterized in that the ribose donor is guanosine and the tem­perature during at least a part of the reaction is at or above 65°C. The method is capable of high produc­tion rates and high concentrations of the final product.
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priorityDate 1987-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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