| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-866 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6857
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39591 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-563
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
| filingDate |
1988-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1990-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0307754-A3 |
| titleOfInvention |
Method for obtaining a papain-free antibody fragment preparation |
| abstract |
A method for obtaining a papain-free F(ab′)₂ nantibody fragment preparation derived from papain ndigested whole IgG antibody employing an antibody nto papain for binding to and removing npapain-associated digestion products from the npreparation. The method is particularly useful for ndigesting whole IgG antibodies which are otherwise nsensitive to pepsin digestion to provide F(ab′)₂ nantibody fragments from which Fab′ antibody nfragments can be obtained having available free nsulfhydryl groups in the hinge region. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8323903-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8535894-B2 |
| priorityDate |
1987-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |