| abstract |
A novel process is described for the production of substituted 1,3,4,9-tetrahydropyrano[3,4-b-]indole-1-acetic acids having useful analgesic and anti-inflammatory activity and having the formula (I)n wherein R¹ is lower alkyl, R⁴ and R⁵ are hydrogen, lower alkyl or halogen and R² is hydrogen, 4-halogen 2,4-dihalo, 3-trifluoromethyl or 4-methoxy via the intermediate of formula |