abstract |
The invention relates to a device for the controlled delivery of nitroglycerin to human or animal skin, preferably in plaster form, with a backing layer impermeable to nitroglycerin, a pressure-sensitive adhesive containing nitroglycerin in a uniform or non-uniform distribution and, if appropriate, a reservoir which is impermeable to nitroglycerin, Removable protective layer, the reservoir being produced using hot-melt pressure sensitive adhesives with a processing temperature of 40 and 80 degrees Celsius, preferably 40 and 60 degrees Celsius and particularly preferably between 40 and 55 degrees Celsius, and a process for their production with continuous or discontinuous application of nitroglycerin containing melted hot melt adhesive at a temperature of the hot melt adhesive between 40 and 80 degrees Celsius, preferably 40 to 60 degrees Celsius and particularly preferably 45 to 55 degrees Celsius on a carrier un d If necessary, attach the protective layer material. |