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filingDate 1988-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a33bd864e7f3ca2b691aaa60de64f1bc
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publicationDate 1989-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0304238-A2
titleOfInvention Method for detecting and confirming the presence of antibodies
abstract A non-competitive method for detecting the presence of Hepatitis B core antibody (anti-HBc) in a biological fluid is provided. The method comprises contacting the fluid with an insoluble surface coated with hepatitis B core antigen (HBcAg). The surface is then contacted with a mixture of a labeled antibody specific for human IgG and a labeled antibody specific for human IgM. Detection of the label bound to the insoluble surface indicates the presence of anti-HBc in the sample. A method for confirming the presence of an antibody of interest in a biological fluid is also provided.
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