http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0303546-A3

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filingDate 1988-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1990-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0303546-A3
titleOfInvention O-alkylation process for n-(hydroxy)aralkyl phenyl ethanol amines
abstract Process for the preparation of compounds of formula n<IMAGE>n in which X denotes hydrogen, a halogen, a trifluoromethyl group or a lower alkyl group; W denotes methyl, Q denotes hydrogen or W and Q together form an ethylene group and R' denotes a lower alkyl group, characterised in that the amino group of the phenol corresponding to the compound of formula I is protected, the compound thus obtained is subjected to an alkylation with a compound of formula Hal-CH2-COOR', where R' is as defined in the case of formula I and Hal is chlorine, bromine or iodine, and the amino group of the product thus obtained is then deblocked.
priorityDate 1987-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 33.