Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69acaefdafb0c568e4a8788890c3de74 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2984 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-829 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate |
1987-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60f57b7e5b534c2e7efcc7082d788658 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a503a2f485a9f040e342dc5c3e73360e |
publicationDate |
1988-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0296212-A1 |
titleOfInvention |
LIPOSOME WITH INCREASED CIRCULATION TIME. |
abstract |
A liposome composition containing a trapped pharmaceutical agent, characterized by (a) liposomes having dimensions primarily between about 0.07 and 0.5 microns; (b) at least about 50 mole% of a lipid stiffening the membrane, such as sphingomyelin or neutral phospholipids with mainly saturated acyl chains; (c) between about 5 and 20 mole% of a glycolipid selected from the group consisting of ganglioside GM1, phosphatidylinositol and the galactocerebroside sulfate ester. Liposomes in which a drug is trapped are administered as a suspension intravenously as a therapeutic treatment; these liposomes have an extended circulation time in the blood. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-668934-B2 |
priorityDate |
1986-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |