| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-814
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-816
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-815 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06139
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-078
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
| filingDate |
1983-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1990-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0295724-A3 |
| titleOfInvention |
Biosynthesis of unnatural cephalosporins |
| abstract |
A peptide precursor of the ACV (aminoadipyl-cysteinyl-nvaline) type, in which the valine moiety may be replaced nby any readily available amino acid may be converted ninto a cephalosporin of the type n nwhere R₁ is H, lower alkyl or functionalized carboxylic ngroup and R₂ is H or lower alkyl, by reacting the nprecursor with novel cyclase, epimerase and ring nexpansion enzymes isolated from a cell-free extract nof a prokaryotic organism such as Streptomyces clavuligerus . nThe three novel enzymes may be immobilized separately nor together on a suitable support medium and the conversion nmay be carried out in a continuous mode. |
| priorityDate |
1982-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |