| abstract |
Compounds of the formula (I):n wherein X is H, F, Cl, Br, I, C₁₋₄alkyl, CN, NO₂, SO₂NH₂, COOH, OH, CHO, C₁₋₄alkoxy, CH₂OH, CH₂OC₁₋₄alkyl, CF₃, C₂F₅, C₃F₇, SO₂CH₃, SO₂CF₃, or CO₂C a H 2a+1 wherein a is 1-5, or any accessible combination thereof of up to 5 substituents; R and R′ independently are H or C₁₋₄alkyl; and n is 1-5; or any pharmaceutically acceptable salt or hydrate thereof, processes for their preparation; intermediates used in their preparation; compositions containing them and their use in therapy as dopamine-β-hydroxylase inhibitors. |