| abstract |
It is a depolymerization process of Heparin to obtain a Heparin of low molecular weight, constituted by a mixture of Heparin fragments of optimal composition, leading to its goal depolarization by treating a single salt of hepatarin cuaternary ammonia with a cuaternary ammonium diroxide in a non-hydroxylated solvent, at a temperature between 10 and 60 ยบ C., subjecting the product obtained to a moderate treatment with sodium borohydride and potassium permanganate. |