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filingDate 1988-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1992-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1992-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0286581-B1
titleOfInvention Buccal administration of estrogens
abstract An adequate blood plasma level of 17-beta-estradiol or ethinyl estradiol is attained in a patient in need of estrogen therapy by administration of a dose of 17-beta-estradiol or ethinyl estradiol or a pharmaceutically acceptable ester thereof not greater than 150 micrograms into the vestibule of the buccal cavity of the patient and maintaining the dose in contact with the oral mucosa for a period of time sufficient for transmucosal absorption of a sufficient amount of estrogen to produce a therapeutically effective plasma concentration of estrogen.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10294873-B2
priorityDate 1987-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 34.