| abstract |
There is disclosed a novel process to produce 2ʹ,3ʹ-dideoxynucleosides such as, for example, 2ʹ,3ʹ-dideoxycytidine, in high yields. More particularly, the various stereoisomers of 2ʹ,3ʹ-dideoxynucleosides are obtained. The α- and β-(L)-2ʹ,3ʹ-dideoxynucleosides and certain α-(D)-2ʹ,3ʹ-dideoxynucleosides are obtained as stereochemically pure compounds not heretofore obtained. The compounds so produced are useful as antiviral and antibiotic agents. |