| abstract |
A therapeutic and prophylactic agent for peptic ulcers comprising as an effective ingredient a cyclohexane derivative represented by general formula (I):n wherein A represents a group shown by formula, >CH₂,n X represents ethynylene, vinylene or ethylene, Y represents oxo or a hydroxy group; nR¹, R³, R⁴ and R⁵ each represents a hydrogen atom or substituted or unsubstituted alkyl; R² represents a hydrogen atom or substituted or unsubstituted alkyl or a group shown by -OR⁸; R⁶ represents a hydrogen atom, oxo or a group shown by -OR⁸; R⁷ represents a hydrogen atom or a group shown by -OR⁸, and R⁸ represents a hydrogen atom or an organic residue, and a pharmaceutically acceptable additive. n Such derivatives are also provided for use as a medicament, particularly for the treatment or prevention of peptic ulcers. n The use of such derivatives for the manufacture of a medicament having therapeutic and preventative value is also provided. |