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publicationDate 1996-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0280570-B1
titleOfInvention Glycopeptide recovery process
abstract A process for recovering vancomycin-type glycopeptide antibiotics which comprises 1) commingling the fermentation medium in which the antibiotic is produced with a polystyrene divinylbenzene resin such as Dow XFS-43278.00, 2) separating the resin from the medium and 3) eluting the antibiotic from the resin. This improvement avoids preliminary filtration and pH adjustment of the broth, simplifies waste-disposal problems and eliminates antibiotic losses due to mycelial adsorption and filtration.
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