| abstract |
The present invention relates to compounds which are allenyl amines, more specifically, β-ethenylidene-(substituted)ethanamines, possessing antihypertensive activity. They are prepared by a novel reaction of a protected N,N-bis-(trimethylsilyl)-4-methoxy-2-butynylamine compound with a metallo-organic compound, with subsequent removal of the silyl protecting groups to provide the desired compound. |