http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0278603-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b9f373878f16dc291ff597162e9b344 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-54 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-54 |
| filingDate | 1988-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0148dbde38ef5179a3a2f6d7622764da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17cffbcc4a02f839ac5856dcb0f51b18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_711e3ecef2eafdec16651f8e35a5c182 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05fdc6fac2468c2d7ce425572d944830 |
| publicationDate | 1988-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0278603-A1 |
| titleOfInvention | Condensed pyrazole derivatives and process for their preparation |
| abstract | The invention relates to compounds having the general formula (I)n whereinn Z represents a C 2 -C 6 alkylene chain or a -CH = CH-CH = group or an -E-CHR 4 -(CH 2 ) p -group, in which p is zero, 1 or 2; E represents an oxygen atom or a n group, wherein q is zero, 1 or 2; and R 4 is hydrogen or C 1 -C 3 alkyl; R, represents C,-C 6 alkyl, benzyl, pyridyl or phenyl, the phenyl being unsubstituted or substituted by one or two substituents chosen independently from halogen, trifluoromethyl, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, nitro, amino, formylamino and C 2 -C 8 alkanoylamino; each of R2 and R 3 is independently:n a) hydrogen, halogen or C,-C 6 alkyl; b) hydroxy, C,-C 6 alkoxy or C 3 -C 4 alkenyloxy; or c) nitro, amino, formylamino or C 2 -C 8 alkanoylamino; nand W represents: a') a n group, wherein n is 1 or 2 and R represents hydrogen or C 1 -C 6 alkyl; nor b') a n group, wherein Q represents hydrogen, carboxy, CONH 2 , C 2 -C 7 alkoxycarbonyl or an or an group, wherein R a represents hydrogen or C,-C2 o alkyl and R b represents C 1 -C 20 alkyl or a -(CH 2 ) m -R 5 group, wherein m is zero, 1 or 2 and R s is:n a") C 5 -C 8 cycloalkyl; b") pyridyl unsubstituted or substituted by one or two substituents chosen independently from halogen, C,-C 6 alkyl and C 1 -C 6 alkoxy; or c") phenyl unsubstituted or substituted by one or two substituents independently chosen from halogen, CF 3 , C 1 -C 6 alkyl, C 1 -C 6 alkoxy, amino, nitro, formylamino, C 2 -C 8 alkanoylamino, di(C 1 -C 6 alkyl)amino, hydroxy, formyloxy and C 2 -C 8 alkanoyloxy, and the pharmaceutically acceptable salts thereof, which possess immunomodulating activity and are useful e.g. in the treatment of neoplastic diseases and acute and chronic infections of both bacterial and viral origin in mammals. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5196445-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1051826-C http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5352676-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5260328-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9011760-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9906374-A1 |
| priorityDate | 1987-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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