| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f450229758aabc033229c40f1b6725de |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2310-00293 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-28 |
| filingDate |
1988-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f88eeb6d002c91b4023b22cf00fc0db0 |
| publicationDate |
1988-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0278583-A2 |
| titleOfInvention |
Calcium phosphate bone substitute materials |
| abstract |
Calcium phosphates useful as bone substitute material or for the manufacture of prosthetic devices have been prepared from calcium hydroxyapatite material which has uniformly permeable microporous structure chacterized by a substantially uniform pore volume in the range from about 10 to about 90% and by a pronounced three-dimensional fenestrate structure corresponding to the microstructure of the porous carbonate echinoderm or scleractinian coral skeletal material of marine life by reacting said calcium hydroxyapatite material which has a calcium to phosphorus atomic ratio of about 1.66 with a phosphate-contributing or phosphorus-contributing moiety or with a calcium-contributing or calcium oxide-contributing moiety so as to alter the calcium to phosphorus Ca/P atomic ratio to yield a calcium phosphate material retaining the above-described microstructure of the porous carbonate echinoderm or scleractinian coral skeletal material but having a calcium to phosphorus Ca/P atomic ratio less than or greater than 1.6, such as a calcium phosphate material comprising dicalcium phosphate and/or tricalcium phosphate and having a calcium to phosphorus Ca/P atomic ratio in the range 1.0-1.5 when the calcium hydroxyapatite material is reacted with said phosphate-contributing or phosporus-contributing moiety or a calcium phosphate material having a calcium to phosphorus Ca/P atomic ratio greater than 1.66 up to 2.0 when the calcium hydroxyapatite material is reacted with said calcium-contributing or calcium oxide-contributing moiety and comprising tetracalcium phosphate. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2018207988-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9503074-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2040626-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7008450-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2370837-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2370837-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0156515-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7514024-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0156515-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6626950-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6743232-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-3903695-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2654001-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0395187-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BE-1024778-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2018207988-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6575986-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0395187-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018130686-A1 |
| priorityDate |
1987-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |