| abstract |
The novel class of xanthenone-4-acetic acids represented by the general formula (I)n where R₁ represents up to two of the groups lower alkyl, halogen, CF₃, CN, NO₂, NH₂, CH₂COOH, OR₂, OH, NHCOR₂, NHSO₂R₂, SR₂, SO₂R₂, CH₂CONHR₂ or NHR₂ (where R₂ is lower alkyl optionally substituted with hydroxy, amino or methoxy functions), at any of the positions 1-8 which are available, R₁ may also represent the substitution of an aza (-N=) group for one or two of the methine (-CH=) groups in the carbocyclic rings and two of R₁ on any two available adjacent positions may also represent the grouping -CH=CH-CH=CH- to form an additional fused benzene ring; nor a basic addition salts thereof, possess antitumour and antibacterial properties. |