abstract |
Topical anti-inflammatory/analgesic pharmaceutical compositions for use in tape form which contain piroxicam as the essential active ingredient therein are disclosed. These compositions include the active ingredient in an aqueous dispersion with or without an organic solvent in an alkaline agent in conjunction with an aqueous adhesive base, said compositions having a pH value of from about 4.0 to about 9.0. These novel formulations in tape form are characterized by excellent applicability on the skin, good skin permeability and good stability. A preferred embodiment involves an acrylic acid ester resin emulsion as the aqueous adhesive base, an alkanolamine or ammonium hydroxide as the alkaline agent and benzyl alcohol, propylene glycol or crotamiton as the solubilizing agent. |