http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0274343-A1

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filingDate 1987-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8425bfeee574501c8564c3ca7957e9bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd77a64ac1349aea10f718c0693d758f
publicationDate 1988-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0274343-A1
titleOfInvention A system of reactants involving an apo-enzyme useful in immunological analysis and a method for carrying out immunoassays with this system
abstract A quick and simple immunoassay technique applicable to the determina­tion of large molecules like proteins, polynucleotides and others involves labelling competitive immuno-species with an enzyme as signal generator. This enzyme can be converted to the corresponding apo-enzyme form and its regeneration, upon addition of a suitable co-factor, is inhibited by com­plexation when the labelled specie is reacted with its immunopartner. The degree of complexation is therefore ascertained by measuring the extent of regenerated activity.
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priorityDate 1987-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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