http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0269512-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
filingDate | 1987-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10292d786dc5c931600d64c5eb16da98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf8bf1f6d5a5087d9060e556e4ac5aca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d64bed7cd06d6ddbc35b5eefe7e5f6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20ff0b83e2fb0b4cf01340dbcfeaf51f |
publicationDate | 1988-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0269512-A1 |
titleOfInvention | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them |
abstract | - Ri, R 2 et R 3 représentent H, ou Ri et R 2 représentent H ou CH 3 et n forment un groupe cyclobutyle et R 3 = COOH ; - A et B sont différents et occupent les positions méta et para du noyau benzénique ; l'un représente un groupe hydroxyle et l'autre est choisi parmi les groupesn ainsi que les sels et les esters pharmaceutiquement acceptables desdits dérivés. Elle concerne également un procédé de préparation desdites céphalosporines et leur utilisation en thérapeutique. The subject of the present invention is novel derivatives of cephalosporins with improved pharmacokinetics, corresponding to the general formula: in which : - Ri, R 2 and R 3 represent H, or Ri and R 2 represent H or CH 3 and form a cyclobutyl group and R 3 = COOH; - A and B are different and occupy the meta and para positions of the benzene nucleus; one represents a hydroxyl group and the other is chosen from the groups as well as the pharmaceutically acceptable salts and esters of said derivatives. It also relates to a process for the preparation of said cephalosporins and their use in therapy. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0311521-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5079241-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5189157-A |
priorityDate | 1986-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.