http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0267565-B1
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-08 |
filingDate | 1987-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1991-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1991-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0267565-B1 |
titleOfInvention | One-step process for preparing mixed substituted 1,2-diacyl-sn-glycero-3-phosphocholines |
abstract | Single-stage process for preparing mixed-substituted enantiomerically pure 1,2-diacyl-sn-glycero-3-phosphocholines of general formula I <IMAGE> I in which R1 and R2 are different and independently of each other denote a substituted or unsubstituted C1 to C24-alkyl or C3 to C24-alkenyl radical, by reacting 1-0-triphenylmethyl-2-acyl-sn-glycero-3-phosphocholine of the general formula <IMAGE> II in which T denotes a substituted or unsubstituted triphenylmethyl group and R2 is as defined above, with a reactive carboxylic acid derivative of the general formula R1-CO-X III in which R1 is as defined above and X denotes a carboxylic acid radical, a carbonic acid radical, a sulfonic acid radical or the radical of a fused or unfused five-membered heterocycle having at least two N atoms in the ring, in the presence of a protonic acid, of a Lewis acid or of adducts thereof with electron donors, and isolating the resulting compounds of the general formula I from the reaction mixture. |
priorityDate | 1986-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID88529023 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID235236812 |
Total number of triples: 14.