abstract |
The invention concerns a pharmaceutical compound containing Nifedipine, combined with a physiologically tolerated substance capable of forming a complex with Nifedipine. This increases the solubility of Nifedipine. The complexing substance is preferably a xanthine, especially Theophylline, which gives a surprising synergistic pharmacological combinatory effect. The invention further concerns a pharmaceutical preparation, especially useful for the Nifedipine/Theophylline combination, and a method for producing such preparations. |