http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0262395-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D291-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-335 |
| filingDate | 1987-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9e54335257b5f7afa6f43df570aaff9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33aa6bf9e5c0df6e9fb08e22358d23fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa057e3c6a6980c15e4519e96267477e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3de111f99ae433f8037a7893cbf71ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83eedf1bac0240aea8a96ddfcf47d0a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94d0724fd245e64d3c9070ed2148fcd1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc2f0ff65909d49f80480fc7ca775de3 |
| publicationDate | 1988-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0262395-A2 |
| titleOfInvention | Sulfonamido-ethyl compounds, medicines containing them and process for their preparation |
| abstract | R 1 eine gegebenenfalls durch ein Halogenatom, eine Methyl-oder Methoxygruppe mono-, di-oder trisubstituierte Phenylgruppe, wobei die Substituenten gleich oder verschieden sein können, eine Benzyl-, Nitrophenyl-, Acetamidophenyl-oder Thienylgruppe, R2 eine über eine geradkettige oder verzweigte Alkylengruppe oder über eine Alkenylengruppe gebundene Hydroxycarbonyl-oder Alkoxycarbonylgruppe, wobei jeweils eine Methylengruppe der vorstehend erwähnten Alkylen-oder Alkenylenreste, welche mit dem heterocyclischen Rest verknüpft sein muß, durch eine Hydroxymethylen-oder Carbonylgruppe ersetzt sein kann, oder eine gegebenenfalls im Kohlenstoffgerüst durch eine Alkylgruppe substituierte 4,5-Dihydro-pyridazin-3-on-6-yl-oder Pyridazin-3-on-6-yl-gruppe und X eine gegebenenfalls durch eine Alkylgruppe substituierte Iminogruppe, ein Sauerstcff-oder Schwefelatom bedeuten, deren Enantiomere und deren Salze mit anorganischen oder organischen Basen, falls R 2 eine Hydroxycarbonylgruppe enthält. The invention relates to new sulfonamido-ethyl compounds of the general formula in the R 1 is a phenyl group which is mono-, di- or tri-substituted by a halogen atom, a methyl or methoxy group, where the substituents may be the same or different, a benzyl, nitrophenyl, acetamidophenyl or thienyl group, R2 is a hydroxycarbonyl or alkoxycarbonyl group bonded via a straight-chain or branched alkylene group or via an alkenylene group, it being possible for a methylene group of the abovementioned alkylene or alkenylene radicals, which must be linked to the heterocyclic radical, to be replaced by a hydroxymethylene or carbonyl group, or a 4,5-dihydropyridazin-3-one-6-yl or pyridazin-3-one-6-yl group optionally substituted in the carbon skeleton by an alkyl group and X represents an imino group optionally substituted by an alkyl group, an oxygen or sulfur atom, their enantiomers and their salts with inorganic or organic bases if R 2 contains a hydroxycarbonyl group. n n n The new compounds have valuable pharmacological properties, in particular antithrombotic effects, moreover these are thromboxane antagonists, and can be prepared by processes which are known per se. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4902698-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0363869-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2619109-A1 |
| priorityDate | 1986-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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