abstract |
Composition for coating a biologically active substance which is stable in a medium whose pH is greater than or equal to 5 and which allows the release of the active substance whose pH is less than or equal to 3.5 consisting of a basic amino copolymer (vinylpyridine-styrene copolymer) and of a hydrophobic substance whose melting point is higher than 60 ° C (stearic acid), the hydrophobic substance content being between 50 and 90% of the total mass of the coating, as well as the granules consisting of a core containing the biologically active substance coated with this composition. |