http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0257285-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf57f5d6ba64a8540567bd58450793b6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-655 |
| filingDate | 1987-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7124297439b07ae8c14ae83c4c812ff1 |
| publicationDate | 1988-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0257285-A2 |
| titleOfInvention | Method and compositions for reducing the intraocular pressure of mammals |
| abstract | This invention provides a method for reducing the intraocular pressure in mammals which comprises administering an effective amount of a compound selected from the group consisting of compounds represented by the general formula:n where R₂, R₃ and R₄ are each selected from the group consisting of H and OA; A is H or is selected from the group consisting of hydrocarbyl radicals, e.g. lower alkyl radicals, i.e. methyl, ethyl, propyl etc., or - -R₅, n nwherein R₅ is selected from the group consisting of hydrocarbyl radicals, e.g. alkyl and aromatic residues; n is 2 or 3; and R₁ is selected from the group consisting phenyl and substituted phenyl, e.g. phenyl substituted with hydroxy, nitro, azido, sulfate, sulfonamido, halogen, hydrocarbyl and hetero atom-substituted hydrocarbyl radicals, wherein said heteroatoms are selected from the group consisting of halogen, nitrogen, oxygen, sulfur and phosphorus and said hydrocarbyl radicals comprise from 1 to 12 carbon atoms, with the proviso that at least one of R₂, R₃ and R₄ is H, that at least one of R₂, R₃ and R is not H and that R₂ and R₄ are not both OA; and pharmaceutically-acceptable salts thereof, in an ophthalmic carrier. Preferably, R is phenyl or 3 or 4 hydroxyphenyl. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6169116-B1 |
| priorityDate | 1986-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 191.