http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0254955-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 1987-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b19edca270387869f95616a00ececf2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7890da0978a4b287b17c1debbd92558a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_566727da82063a61b6976acf98f13407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4210e28ed73b64ce18d675c804a77e95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0480a85f4ad6bc37103475f43c86fa18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2b60a20dae71f26a073943b367309a3 |
| publicationDate | 1988-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0254955-A2 |
| titleOfInvention | Substituted pyrido[2,3-b][1,4]benzodiazepin-6-ones, process for their preparation and medicaments containing these compounds |
| abstract | New substituted pyrido [2,3-b] [1,4] benzodiazepin-6-ones of the general formula I are described in the R¹ is an alkyl group having 1 to 4 carbon atoms, a chlorine atom or a hydrogen atom; R² is a hydrogen atom or a methyl group; R³ and R⁴ each represent a hydrogen atom, a fluorine, chlorine or bromine atom or an alkyl group having 1 to 4 carbon atoms, but with the proviso that at least one of the radicals R¹, R², R³ and R⁴ is different from hydrogen, R⁵ and R⁶ represent the same or different alkyl radicals with up to 6 carbon atoms or together with the nitrogen atom in between form a 4- to 7-membered, saturated, monocyclic, heteroaliphatic ring which can optionally be interrupted by an oxygen atom or by the N-CH₃ group, Z is either a single bond or an oxygen atom, a methylene or 1,2-ethylene group and A is a methylene group in the 2- or 3-position of the heteroaliphatic ring, when linked in the 3-position are also a single bond, and their salts with inorganic or organic acids, processes for the preparation of these compounds and their use in the preparation of medicaments.n n n The compounds of general formula I have favorable effects on the heart rate and are suitable in view of the lack of gastric acid secretion-inhibiting, salivation-inhibiting and mydriatic influences, as well as excellent absorption as vagal pacemakers for the treatment of bradycardias and bradyarrhythmias in human and veterinary medicine. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5002943-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9300906-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0346745-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0306698-A1 |
| priorityDate | 1986-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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