| abstract |
Intermediate compounds of formulan wherein R and R are the same or different and each represents a lower alkoxy or a -N(R 2 ) 2 group and both R 2 , independently, represent a hydrogen atom or a lower alkyl; the carbon atoms marked by an asterisk are both in R or S configuration; allow to obtain enantioselectively the antibiotic known as Fosfomycin by an epoxidation reaction, carried out in the one or two steps, and a hydrolysis reaction. |