| abstract |
A novel isocarbacyclin which is a compound represented by the following formula (I) <CHEM> wherein R<1> represents a hydrogen atom, or a C1-C4 alkyl or alkenyl group; R<2> and R<3> are identical or different and each represents a hydrogen atom, a tri(C2-C7)hydrocarbon -silyl group or a groupp forming an acetal linkage together with the oxygen atom of the hydroxyl group; R<4> represents a hydrogen atom a methyl group or a vinyl group; R<5> represents an unsubstituted linear or branched C3-C8 alkyl group which may be interrupted by an oxygen atom, a substituted linear or branched C1-C5 alkyl group in which the substituent is a C1-C6 alkoxy group or a phenyl, phenoxy or C3-C10 cycloalkyl group which may be substituted further, a phenyl group which may be substituted, a phenoxy group which may be substituted, or a C3-C10 cycloalkyl group which may be substituted; n is 0 or 1; and Ar represents a substituted or unsubstituted phenyl group, its enantiomorph, or a mixture both in an arbitrary ratio. |