| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-325
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
| filingDate |
1987-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1991-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1991-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0247633-B1 |
| titleOfInvention |
Trans-6-[2-(3- or 4-Carboxamido-substituted pyrrol-1-yl)-alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis |
| abstract |
Certain trans-6-[2-(3- or 4-carboxamido-substitutedpyrrol-1-yl)alkyl]-4-hydroxypyran-2-ones and the corresponding ring-opened acids derived therefrom which are potent inhibitors of the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG CoA reductase) and are thus useful hypolipidemic or hypocholesterolemic agents. Pharmaceutical compositions containing such compounds, and a method of inhibiting the biosynthesis of cholesterol employing such pharmaceutical compositions are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7956198-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7129352-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8026377-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6841554-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6737430-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013164257-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6087511-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03008383-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9713614-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7923467-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6274740-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7671216-B2 |
| priorityDate |
1986-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |