abstract |
The invention relates to modified silica, substituted with a variety of nsubstituents. There is provided a product termed primary hydroxyl nsilica where there are attached to the silica substituents bearing a nsingle hydroxyl group. Furthermore there are provided a wide variety of nderivatives of such hydroxy-silica, which are of value in affinity nchromatography and for various other uses. The products combine the nthermal and mechanical stability of the silica used as carrier with the nuseful properties of the substituents. |