http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0244471-A4
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e546052b771ce17a18591c44219ff9f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-706 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
filingDate | 1986-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7c13f344ea81cb66f3ce47080ef047f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2b5a846cb6e56da2413b471166c6458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83ff0ff9623ebaf34670837fac915292 |
publicationDate | 1988-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0244471-A4 |
titleOfInvention | NUCLEIC ACID SAMPLES MARKED WITH LANTHANIDE CHELATE. |
abstract | Nucleic acid probes which are chemically tagged with moieties which chelate the trivalent lanthanides Eu<+3>, Tb<+3> and Sm<+3>. Also provided are methods of making said probes and methods of using the probes in hybridization assays. The probes of the invention are detected, preferably by time-resolved fluorometry, by means of the intense, long-lived fluorescence of Eu<+3>, Tb<+3> and Sm<+3>, particularly in chelates with aromatic trifluoromethyl beta -diketones, such as 2-naphthoyltrifluoroacetone, and synergistic bases, such as tri-n-octylphosphine oxide, when such chelates are in micelles, such as those formed in water with non-ionic detergents such as Triton X-100. |
priorityDate | 1985-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 285.