abstract |
The analysis system for the determination of an analyte comprises liposomes having, bound on the surface, binding molecules relating to the analyte and trapped reporter molecules, as well as a cellulose acetate surface reagent having surface molecules adapted to bind the liposomes to the reagent in proportion to the amount of analyte present. The reagent is prepared according to the invention by treating a cellulose acetate substrate with a base to form a hydrophilic envelope of hydroxyl group on the surface of the substrate, by reacting the modified substrate with a bifunctional reagent in an organic solvent, and by coupling, in an aqueous solution, the surface molecules to the activated substrate. |