http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0243055-A3
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 1987-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1989-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0243055-A3 |
| titleOfInvention | Pyrazolopyridine derivatives, process for their preparation, and pharmaceutical compositions containing them |
| abstract | A compound of the formula (1) or a salt or solvate nthereof: n nin which: nR₀ is hydrogen or C 1-6 alkyl; nR₁ and R₂ are both hydrogen; nor nR₁ is hydrogen, C 1-6 alkyl; and R₂ is CN; CR₅R₆Y nwhere R₅ and R₆ are independently selected from nhydrogen and C 1-4 alkyl and Y is selected from nhydrogen, OR₇ or SR₇ where R₇ is hydrogen, C 1-4 nalkyl or C 2-4 alkanoyl, NR₈R₉ where R₈ and R₉ nare independently hydrogen, C 1-4 alkyl, C 2-4 nalkenyl or C 2-4 alkanoyl or together are C 4-6 npolymethylene; or COR₁₀ where R₁₀ is OH or C 1-4 nalkyl, or COR₁₀ is a pharmaceutically acceptable nester or amide; nor nR₂ is hydrogen, C 1-6 alkyl, or phenyl optionally nsubstituted by halogen, CF₃, C 1-4 alkoxy or C 1-4 nalkyl; and R₁ is CN, CR₅R₆Y or COR₁₀ as defined nfor R₂ above; nor nR₁ and R₂ together form C 3 -C 6 polymethylene noptionally substituted by C 1 -C 4 alkyl; n n nR₃ is -(CH₂) n CO₂R₁₁, -(CH₂) n CONR₁₂R₁₃,-(CH₂) n CN, n-(CH₂) m NHCOR₁₄, -(CH₂) m -O- n-R₁₄ n nwhere a, b, n, m and p are integers and n is 1 to n10, m is 2 to 10, p is 3 to 5, a is 1 to 3, and b nis 1 to 3, nand R₁₁ is hydrogen, C 1-8 alkyl, benzyl or phenyl, nR₁₂ and R₁₃ are independently hydrogen, C 1-6 nalkyl, benzyl or phenyl, or together form C 3-8 nalkylene, R₁₄ is C 1-4 alkyl, benzyl or phenyl and nX is oxygen, sulphur, NH or N-C 1-4 alkyl, and nR₄ is hydrogen; or C 1-4 alkyl or benzyl noptionally substituted in the phenyl ring by one nor two of halogen, CF₃, C 1-4 alkoxy or C 1-4 alkyl, nand is attached at nitrogen atom 1 or 2, a process nfor its preparation and its use as a npharmaceutical. |
| priorityDate | 1986-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.