http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0240717-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_604e07c32377cab416660b10fd8f494c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 |
| filingDate | 1987-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c52eb6adbd1a88bbf76460d03354f4f |
| publicationDate | 1987-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0240717-A2 |
| titleOfInvention | Prevention of mammary carcinoma |
| abstract | To reduce the risk of breast cancer, a drug is periodically administered to young mammals before pregnancy in doses of about 1 microgram to 50 micrograms per killogram of body weight. The drug: (1) competes with and displaces estradiol 17 beta from the mammary gland cells in an effective manner to prevent the possible formation of DNA-damaging epoxide estradiol metabolites; (2) binds to breast tissue to a greater extent than estradiol 17 beta; (3) induces terminal nonlacta- tion differentiation of the mammary gland; (4) is nontoxic and noncarcinogenic; and (5) preferably does not have anti-ovulatory activity. The drug is selected from a group of drugs including: (1)4-OH estradiol; (2) d-equilenin; and (3) 17 alpha ethynyl estriol. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9825626-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6271221-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5576309-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5578589-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0573977-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0215910-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7342004-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0573977-A3 |
| priorityDate | 1986-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.