| abstract |
Pyridoindoles of formula (I)n and their pharmaceutically acceptable acid addition salts, wherein R represents lower alkyl a mono- or bi-cyclic aryl radical or a group of formula R³O-B-[where R³O is (lower)alkoxy,aryl(lower)alkoxy or hydroxy and B is a lower alkylene chain optionally containing one double or triple bond], R¹ and R² which may be the same or different each represent hydrogen, hydroxyl, lower alkyl, lower alkoxy, halo(lower)alkyl, halogen, amino or mono- or di(lower) alkylamino and A, together with the carbon atom to which it is attached, represents 5, 6 or 7 membered saturated carbocyclic or heterocyclic ring,are useful as hypoglycaemics. |