abstract |
Introduction of an erythropoietin gene into specific cells originating from an animal such as mouse or hamster through the medium of a particularly prepared vector will permit the preparation of cells capable of producing erythropoietin constitutively in an efficient manner and cultivation of the cells thus-prepared will produce erythropoietin in a high yield. Further, the erythropoietin thus-produced can be isolated in a high purity by means of an immunoaffinity column containing a monoclonal antibody against human erythropoietin. |