| abstract |
The compound of the formulan wherein R' is hydrogen, methoxy or trifluoromethyl, R 2 and R 3 are the same or different and are each hydrogen or methyl, R 4 is a fluorinated lower alkyl having 2 to 5 carbon atoms and 1 to 11 fluorine atoms and X- is a pharmaceutically acceptable anion, respectively, possesses both strong antisecretory activity and gastric mucosal protective activity, which is produced by reacting a pyridine derivative of the formulan wherein R', R 2 , R 3 and R 4 have the same meaning as defined above, with an acid. |