http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0233483-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 |
| filingDate | 1987-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b0cfc9652b26efd5f555a5cd863c239 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5424f6ac861405a7a1585d285ad862e |
| publicationDate | 1987-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0233483-A2 |
| titleOfInvention | Pyrrolo[1,2-a][4,1]benzoxazepines, process for their preparation, pharmaceutical compositions containing these compounds and therapeutical use |
| abstract | The invention relates to novel gastrointestinal secretion-inhibiting and antidiarrheal active compounds of the general formula where n is an integer 1, 2, 3 or 4; R 1 represents hydrogen, nisderalkyl, halogen, trifluoromethyl, hydroxy or lower alkoxy; R 2 is hydrogen or lower alkyl; R 3 represents hydrogen, lower alkyl or halogen; R 4 amino, lower alkylamino, di-lower alkylamino, morpholino, N-lower alkyl or N-arylpiperazino, pyrrolidino, piperidino or substituted piperidino selected from wherein R s represents hydrogen, halogen or lower alkyl; and salts, and especially pharmaceutically acceptable salts of all of these compounds. You can, for example, by condensation of an amine of the formula III wherein R 4 has the meaning given above and H is bonded to the nitrogen atom of group R 4 , with a compound of formula IV wherein n, R 1 R 2 and R 3 have the meaning given under formula and X is a reactive esterified hydroxy group, are prepared. |
| priorityDate | 1986-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.