| abstract |
Compounds of structure (I)n in which Ar is furyl, thienyl, phenyl or phenyl which is substituted with 1 or 2 methoxy, hydroxy, halo or methyl groups; R is hydrogen, C 3-6 allyl or C 1-4 -alkyl; and R¹ and R² are, each, hydrogen, C 1-4 alkoxy, hydroxy, halo or trifluoromethyl, at least one of R¹ and R² being other than hydrogen, and pharmaceutically acceptable acid addition salts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as dopamine antagonists. |