| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c62268de3e92657ca5b9adcac4778225 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5255 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-525 |
| filingDate |
1986-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88c468285a117a5052ff49f473db8d98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9673e347aaf7b0656284e05ae0702e11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ad2990e35abfce19d61274d74dc8640
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdfaaf0c77f6fad87f98ec4f3d08238e |
| publicationDate |
1987-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0230781-A2 |
| titleOfInvention |
Lymphotoxin gene, method for its production, and lymphotoxin |
| abstract |
Lymphotoxin-producing human T-cell hybridomas are incubated in a medium containing phorbol myristate acetate, concanavalin A or a mixture thereof, the resulting cells are fractionated by sucrose density gradient centrifugation method to isolate a messenger RNA in l2.6S to l4.6S fractions, and a gene containing a part encoding a polypeptide having a lymphotoxin-activity is prepared from the messenger RNA. The gene is represented by the base sequence of the Table l as herein given. Using the present gene, a new lymphotoxin having the amino acid sequence (I) or (II) as given herein can be obtained by genetic engineering technology. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0314094-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0272894-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2217326-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2217326-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5175268-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0272894-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5188969-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0314094-A2 |
| priorityDate |
1985-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |