| abstract |
The invention relates to a pharmaceutical composition, in particular in tablet form, with sustained release of the active component. n The pharmaceutical composition of the invention contains besides the active component a sugar ester of higher C 10 -C 15 fatty acids in a suitable ratio to each other together with other suitable substances. n Usually, the sugar ester is a sucro ester and preferably sucrose monopalmitate. n Advantageously, the pharmaceutical composition of the invention besides the active component and the sugar ester furthermore contains a substance to control the release of the active component in the gastro-intestinal canal, such as PVP or a higher fatty acid (C 10 -C 25 ), a higher alcohol (C 10 -C 25 ) or fat (for instance stearinic acid). n Usually, the active component is a non-stereoidal anti-inflammatory compound and preferably Ibuprofen. n The invention also relates to a process for the preparation of the above pharmaceutical composition. |