| abstract |
Compounds of formula (1) n<CHEM>n and pharmaceutically and veterinarily acceptable salts thereof, wherein each R<1> is, independently, alkyl, alkoxy, halogen, amino, hydroxy, nitro, cyano, carboxyl, trifluoromethyl, ethyl carboxylate, or hydrogen; m is 0, 1 or 2, inclusive; and A is either -(CH2)n-C(O)R<2>, where n is 1 to 5 and R<2> is hydroxy, alkoxy, araloxy, aralkyl, amino, alkyl, alkylamino, dialkylamino, cycloalkylamino, or morpholino; or A is alkyl, hydroxyalkyl, alkoxyalkyl, aralkoxyalkyl, aryl, aralkyl, or cycloalkyl, are useful as cholecystokinin antagonists in the treatment of acute pancreatitis, gastric, peptic and duodenal ulcers and in the suppression of appetite. |