http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0227252-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7084 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
filingDate | 1986-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1991-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1991-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0227252-B1 |
titleOfInvention | Medical device for pulsatile transdermal delivery of biologically active agents |
abstract | The present invention relates to A medical device for the pulsatile administration of a drug through intact skin at a first steady state flux during a first delivery period and a second steady state flux during a second delivery period, said first flux being substantially higher than said second flux; said first and second delivery periods comprising a substantial portion of a predetermined administration period, characterised in that said device comprises:n a) a reservoir of said drug containing an amount of drug sufficient to adminster drug at said first and second steady state fluxes throughout said administration period;n b) a reservoir of a skin permeation enhancer for said drug; said reservoir containing an amount of said permeation enhancer sufficient to permit administration of said drug at said first flux only through said first delivery period; andn c) means for maintaining said device on the skin in drug and permeation enhancer transferring relationship thereto. |
priorityDate | 1985-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.