| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05ff905fdc49089f5f25746eaeb40190 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-367 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-367
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-00 |
| filingDate |
1986-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f9a55f0b1ed9a5beb13c4031d50aa33 |
| publicationDate |
1987-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0226161-A1 |
| titleOfInvention |
Improved process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid |
| abstract |
An improved two-step process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid (gemfibrozil) which regularly affords gembibrozil in overall yields in excess of 80% comprises reacting an alkali metal salt of a lower alkyl ester of 2-methylpropanoic acid with 1,3-dibromopropane or 1-bromo-3-chloropropane in a polar aprotic solvent such as tetrahydrofuran, and then reacting the intermediate thus formed with an alkali metal salt of 2,5-dimethylphenol in a mixed toluene/dimethylsulfoxide solvent system. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2036438-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020212955-A1 |
| priorityDate |
1985-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |