http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0225386-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ccb9ef26f43ac2907a5b97404cb05707 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90a89ac945b13b12c19821f7d438e8d4 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-18 |
filingDate | 1986-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f844a2005ee1e35d36b13221925c27e3 |
publicationDate | 1987-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0225386-A1 |
titleOfInvention | Bradykinin antagonist peptides |
abstract | Replacing L-Pro at position 7 of the hormonal peptide bradyquinine or other substituted analogs of bradyquinine with an aromatic amino acid of configuration D transforms the bradyquinine agonists into a bradyquinine antagonist. Other modifications of other positions in these innovative 7-position modified bradyquinine antagonists increase the enzyme resistance, potency and / or antagonist specificity of these novel bradyquinine antagonists. The analogs produced are useful for treating pathological conditions or diseases of the body of humans and mammals due to an excess of bradyquinine or related quinines produced or injected, for example by bites, into the body. |
priorityDate | 1985-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 205.