abstract |
A process for producing oxiracetam (4-hydroxy-2-oxo-1-pyrroldineacetamide) useful as an agent for improving brain metabolism, under mild conditions and in a single process, comprises reacting glycinamide with a butyric acid ester expressed by the formula wherein A represents a halogen atom and B represents a hydroxyl group, or A and B together form an epoxy group, and R represents an alkyl group. |