| abstract |
The new N-substituted diphenylpiperidines of the formula <IMAGE> wherein R¹ is CH, C = CH or CH-CH2 R² alkylene or CO- (CH2) n, n 0 to 11, R³ and R <4> are hydrogen, halogen or lower alkoxy , Het are pyridyl, pyrimidinyl or imidazolyl, and salts thereof with pharmaceutically acceptable acids can be used to lower insulin levels and to treat obesity. They can be prepared from corresponding N-unsubstituted diphenylpiperidines. |